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Blood Pressure

When to get it: Annually beginning in his 30s

Why it counts: “This is the most important piece of data available because it clearly shows if there is something affecting the arteries,” says Michael Roizen, MD, chair of the Cleveland Clinic’s Wellness Institute and coauthor of the YOU: The Owner’s Manual series. Ideal goal: 115/75 or less.

Cholesterol and Triglycerides Blood Test (including LDL/HDL cholesterol ratio and triglycerides/HDL ratio)

When to get it: Every 5 years up to age 45, then annually

Why it counts: The triglyceride/HDL ratio warns of not only potential cardiovascular disease but also potential liver disease, says Dr. Roizen.

C-reactive Protein (CRP) Blood Test

When to get it: Consider starting in his 40s

Why it counts: If he has heart disease risk factors, a CRP test, which measures inflammation, may be useful. Some experts, like Dr. Roizen, recommend that everyone get this test annually because it can give your doc a warning about heart, prostate or liver problems.

Thyroid Function Blood Test

When to get it: Baseline at about age 20, then every 5 years until age 60, then annually

Why it counts: Low thyroid function can lead to a variety of conditions, including constipation, depression and high cholesterol.

Colonoscopy

When to get it: Beginning at age 50, then every 5 to 10 years after that if everything looks normal (earlier or frequent screenings may be recommended for those with a family history of colorectal cancer)

Why it counts: Colorectal cancer is the second leading cause of cancer-related deaths among men.

Prostate-Specific Antigen Blood Test

When to get it: Baseline at age 40, follow-ups at age 50 and then annually for 15 years.

Why it counts: PSA tests are currently in the crossfire between major advocacy organizations. Talk to your doc about what works best for you.

Digital Rectal Exam (DRE)

When to get it: Annually starting at age 40

Why it counts: The DRE is less effective than PSA blood tests at finding prostate cancer, but it sometimes finds the disease in men with normal PSA levels.