An elevated erythrocyte sedimentation rate (ESR) or a high level of C-reactive protein (CRP) in your blood may indicate inflammation somewhere in your body. However, it's not likely related to your fibromyalgia, since fibromyalgia isn't an inflammatory condition. Various conditions can cause elevated ESR and CRP levels, including:

  • Infection
  • Rheumatoid arthritis
  • Inflammatory bowel disease
  • Cardiovascular disease
  • Cancer

To better understand the clinical significance of your elevated ESR and CRP levels, consult your doctor.